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1

Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs

Savvas Kleanthous, Alan D. Borthwick, David Brown, Cynthia L. Burns-Kurtis, Matthew Campbell, Laiq Chaudry, Chuen Chan, Marie-Olive Clarte, Máire A. Convery, John D. Harling, Eric Hortense, Wendy R. I

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 535 KB

english, 2010

2

Structure and property based design of factor Xa inhibitors: Biaryl pyrrolidin-2-ones incorporating basic heterocyclic motifs

Robert J. Young, Alan D. Borthwick, David Brown, Cynthia L. Burns-Kurtis, Matthew Campbell, Chuen Chan, Marie Charbaut, Máire A. Convery, Hawa Diallo, Eric Hortense, Wendy R. Irving, Henry A. Kelly, N

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 258 KB

english, 2008

3

Structure and property based design of factor Xa inhibitors: Pyrrolidin-2-ones with aminoindane and phenylpyrrolidine P4 motifs

Robert J. Young, Carl Adams, Mike Blows, David Brown, Cynthia L. Burns-Kurtis, Chuen Chan, Laiq Chaudry, Máire A. Convery, David E. Davies, Anne M. Exall, Graham Foster, John D. Harling, Eric Hortense

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 616 KB

english, 2011

4

Denaturant sensitive regions in creatine kinase identified by hydrogen/deuterium exchange

Hortense Mazon, Olivier Marcillat, Eric Forest, Christian Vial

Journal:

Rapid Communications in Mass Spectrometry

Year:

2005

Language:

english

File:

PDF, 472 KB

english, 2005

5

Hydrogen/deuterium exchange studies of native rabbit MM-CK dynamics

Hortense Mazon, Olivier Marcillat, Eric Forest, Christian Vial

Journal:

Protein Science

Year:

2004

Language:

english

File:

PDF, 333 KB

english, 2004

6

Local dynamics measured by hydrogen/deuterium exchange and mass spectrometry of creatine kinase digested by two proteases

Hortense Mazon, Olivier Marcillat, Eric Forest, Christian Vial

Journal:

Year:

2005

Language:

english

File:

PDF, 548 KB

english, 2005

7

Conformational Dynamics of the GdmHCl-Induced Molten Globule State of Creatine Kinase Monitored by Hydrogen Exchange and Mass Spectrometry

Mazon, Hortense, Marcillat, Olivier, Forest, Eric, Smith, David L., Vial, Christian

Journal:

Year:

2004

Language:

english

File:

PDF, 140 KB

english, 2004

8

Role of C-Terminal Sequences in the Folding of Muscle Creatine Kinase

Mazon, Hortense, Marcillat, Olivier, Vial, Christian, Clottes, Eric

Journal:

Year:

2002

Language:

english

File:

PDF, 95 KB

english, 2002

9

Changes in MM-CK Conformational Mobility upon Formation of the ADP−Mg 2+ −NO 3- −Creatine Transition State Analogue Complex As Detected by Hydrogen/Deuterium Exchange

Mazon, Hortense, Marcillat, Olivier, Forest, Eric, Vial, Christian

Journal:

Year:

2003

Language:

english

File:

PDF, 239 KB

english, 2003

10

Full genome characterization of human Rotavirus A strains isolated in Cameroon, 2010–2011: Diverse combinations of the G and P genes and lack of reassortment of the backbone genes

Ndze, Valentine Ngum, Esona, Mathew Dioh, Achidi, Eric Akum, Gonsu, Kamga Hortense, Dóró, Renáta, Marton, Szilvia, Farkas, Szilvia, Ngeng, Marxcel Bong, Ngu, Akum Felix, Obama-Abena, Marie Therese, Bá

Journal:

Infection, Genetics and Evolution

Year:

2014

Language:

english

File:

PDF, 1.07 MB

english, 2014

11

Is Drinking Water in Abidjan, Côte d'Ivoire, Safe for Infant Formula?

Dunne, Eileen F., Angoran-Bénié, Hortense, Kamelan-Tano, Akoua, Sibailly, Toussaint S., Monga, Ben B., Kouadio, Luc, Roels, Thierry H., Wiktor, Stefan Z., Lackritz, Eve M., Mintz, Eric D., Luby, Steve

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2001

File:

PDF, 1.75 MB

2001

12

Is Drinking Water in Abidjan, Côte d'Ivoire, Safe for Infant Formula?

Dunne, Eileen F., Angoran-Bénié, Hortense, Kamelan-Tano, Akoua, Sibailly, Toussaint S., Monga, Ben B., Kouadio, Luc, Roels, Thierry H., Wiktor, Stefan Z., Lackritz, Eve M., Mintz, Eric D., Luby, Steve

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2001

File:

PDF, 1.75 MB

2001

13

Identification of Nedotepa curta Dmitriev as a potential vector of the Côte d’Ivoire lethal yellowing phytoplasma in coconut palms sole or in mixed infection with a ‘ Candidatus Phytoplasma asteris’-related strain

Kwadjo, Koffi Eric, Beugré, N.'Djiha Isabelle, Dietrich, Christopher H., Thierry Kodjo, Adaba Tano, Atta Diallo, Hortense, Yankey, Ndede, Dery, Sylvester, Wilson, Michael, Konan Konan, Jean Louis, Con

Journal:

Crop Protection

Year:

2018

Language:

english

File:

PDF, 2.47 MB

english, 2018

14

Depdc5 knockdown causes mTOR-dependent motor hyperactivity in zebrafish

de Calbiac, Hortense, Dabacan, Adriana, Marsan, Elise, Tostivint, Hervé, Devienne, Gabrielle, Ishida, Saeko, Leguern, Eric, Baulac, Stéphanie, Muresan, Raul C., Kabashi, Edor, Ciura, Sorana

Journal:

Annals of Clinical and Translational Neurology

Year:

2018

Language:

english

File:

PDF, 959 KB

english, 2018

15

Données d’efficacité et de toxicité des immunothérapies anti cancéreuses chez le sujet âgé – 5e journée de pharmacologie des anti-tumoraux

Gaultier De Saint Basile, Hortense, Poisson, Caroline, Arrondeau, Jennifer, Boudou-Rouquette, Pascaline, Goldwasser, François, Tartour, Eric, De Guillebon, Eléonore

Journal:

Bulletin du Cancer

Year:

2018

Language:

french

File:

PDF, 821 KB

french, 2018

16

Données d’efficacité et de toxicité des immunothérapies anti cancéreuses chez le sujet âgé – 5e journée de pharmacologie des anti-tumoraux

Gaultier De Saint Basile, Hortense, Poisson, Caroline, Arrondeau, Jennifer, Boudou-Rouquette, Pascaline, Goldwasser, François, Tartour, Eric, De Guillebon, Eléonore

Journal:

Bulletin du Cancer

Year:

2018

File:

PDF, 821 KB

2018